A Study in Healthy Subjects to Investigate Pharmacokinetics of AZD5423 When Administered in Different Ways

PHASE1CompletedINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

August 31, 2012

Primary Completion Date

December 31, 2012

Study Completion Date

December 31, 2012

Conditions
Bioavailability and AUC
Interventions
DRUG

AZD5423

solution for injection, administered as intravenous infusion Corr to total dose of 250 µg AZD5423

DRUG

AZD5423

nebuliser suspension, inhaled via Spira, corr to approximately 300 µg lung deposited dose AZD5423

DRUG

AZD5423

nebuliser suspension, inhaled via I-neb, corr to approximately 300 µg lung deposited dose AZD5423

DRUG

AZD5423

nebuliser suspension to be administered orally, corr to a total dose of 1200 µg AZD5423

DRUG

AZD5423

dry powder inhaled via Turbuhaler, corr to approximately 200 µg lung deposited dose AZD5423

DRUG

AZD5423

dry powder inhaled via New Dry Powder Inhaler, corr to approximately 200 µg lung deposited dose AZD5423

Trial Locations (1)

Unknown

London

Sponsors

Lead Sponsor

All Listed Sponsors
lead

AstraZeneca

INDUSTRY

NCT01635985 - A Study in Healthy Subjects to Investigate Pharmacokinetics of AZD5423 When Administered in Different Ways | Biotech Hunter | Biotech Hunter