30
Participants
Start Date
July 31, 2012
Primary Completion Date
August 31, 2015
CSL362
"CSL362 is humanized monoclonal antibody that targets the alpha chain of the interleukin 3 receptor (IL3Rα; also known as CD123) and is optimised for enhanced activation of antibody-dependent cell-mediated cytotoxicity (ADCC) via natural killer cells.~CSL362 is a sterile solution for injection and will be administered by intravenous infusion to subjects in sequential, escalating dose level cohorts, at doses up to 12.0 mg/kg. CSL362 will be administered every 14 days for a total of 6 infusions per subject. The 6 infusions for each individual subject will contain the same dose of CSL362."
Royal Melbourne Hospital, Parkville
Weill Cornell Medical College, New York
Sidney Kimmel Cancer Center at Johns Hopkins, Baltimore
Robert H. Lurie Comprehensive Cancer Center of Northwestern University Medical School, Chicago
Seattle Cancer Care Alliance, Seattle
Collaborators (1)
Parexel
INDUSTRY
CSL Limited
INDUSTRY