Renal Sympathetic Denervation and Potential Effects on Glucose Metabolism and Cardiovascular Risk-Factors

NACompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

March 31, 2013

Primary Completion Date

December 31, 2015

Study Completion Date

December 31, 2015

Conditions
Hypertension, Resistant to Conventional Therapy
Interventions
PROCEDURE

Renal sympathetic denervation

This is a mini-invasive trans-catheter procedure with access via a 6F introducer in one of the femoral arteries. The renal sympathetic nerves arise from T10-L2, arborize around the renal artery and primarily lie within the adventitia. A specialized radiofrequency (RF) ablation catheter is introduced into the renal arteries, first one side, then on the other. Usually, 4-6 two-minute treatments per artery using a proprietary RF generator with automated low power and built-in safety algorithms are sufficient to ablate the sympathetic afferent and efferent fibers.

Trial Locations (1)

N-9038

University Hospital of North Norway, Tromsø

All Listed Sponsors
collaborator

University of Tromso

OTHER

collaborator

The Royal Norwegian Ministry of Health

OTHER

collaborator

Odd Berg Medical research Foundation

UNKNOWN

lead

University Hospital of North Norway

OTHER

NCT01630928 - Renal Sympathetic Denervation and Potential Effects on Glucose Metabolism and Cardiovascular Risk-Factors | Biotech Hunter | Biotech Hunter