The Influence of Hormonal Changes During Pregnancy on Corneal Biomechanics in Humans

CompletedOBSERVATIONAL
Enrollment

50

Participants

Timeline

Start Date

June 30, 2012

Primary Completion Date

June 30, 2014

Study Completion Date

June 30, 2014

Conditions
Pregnancy
Interventions
DEVICE

Ocular Response Analyzer

To measure corneal biomechanics, specifically corneal hysteresis (CH) and the Corneal Resistance Factor (CRF). The devise measures in a non-contact manner, by analyzing the deformation of the cornea upon a defined pulse of air.

DEVICE

Scheimpflug measurement

A Scheimpflug camera will be used in a non-contact manner to assess topographical data from the anterior and posterior corneal surface as well as detailed data on corneal thickness.

OTHER

Blood sample

A blood sample will be taken at 6 months after surgery to determine the levels of several hormones. The blood needed to détermine hormone levels during pregnancy will be acquired during the routine examinations that are performed during pregnancy. Here, blood is taken routinely and an additional volume is taken for the purpose of this study.

Trial Locations (1)

1211

University Hospital Geneva, Geneva

All Listed Sponsors
lead

University Hospital, Geneva

OTHER

NCT01629264 - The Influence of Hormonal Changes During Pregnancy on Corneal Biomechanics in Humans | Biotech Hunter | Biotech Hunter