660
Participants
Start Date
August 31, 2012
Primary Completion Date
October 31, 2014
Study Completion Date
April 18, 2019
2.0 mg intravitreal aflibercept
Intravitreal injection of 2.0 mg aflibercept at baseline and up to every 4 weeks using defined retreatment criteria.
1.25 mg intravitreal bevacizumab
Intravitreal injection of 1.25 mg bevacizumab at baseline and up to every 4 weeks using defined retreatment criteria.
0.3 mg intravitreal ranibizumab
Intravitreal injection of 0.3 mg ranibizumab (Lucentis™) at baseline and up to every 4 weeks using defined retreatment criteria.
The New York Eye and Ear Infirmary/Faculty Eye Practice, New York
MaculaCare, New York
Mount Sinai School of Medicine, Dept. of Ophthalmology, New York
Retina-Vitreous Surgeons of Central New York, PC, Syracuse
Retina Associates of Western New York, Rochester
University of Rochester, Rochester
Retina Vitrous Consultants, Pittsburgh
University of Pennsylvania Scheie Eye Institute, Philadelphia
Virginia Retina Center, Leesburg
Elman Retina Group, P.A., Baltimore
Retina Institute of Virginia, Richmond
Wake Forest University Eye Center, Winston-Salem
Charlotte Eye, Ear, Nose and Throat Assoc., PA, Charlotte
Western Carolina Retinal Associates, PA, Asheville
Palmetto Retina Center, Columbia
Carolina Retina Center, Columbia
Storm Eye Institute, Medical University of South Carolina, Charleston
Emory Eye Center, Atlanta
Georgia Retina, P.C., Atlanta
Thomas Eye Group, Atlanta
Southeast Retina Center, P.C., Augusta
Magruder Eye Institute, Orlando
Fort Lauderdale Eye Institute, Plantation
Retina Group of Florida, Fort Lauderdale
Retina Associates of Florida, P.A., Tampa
Gulf Coast Retina Center, Clearwater
Central Florida Retina Institute, Lakeland
National Ophthalmic Research Institute, Fort Myers
Sarasota Retina Institute, Sarasota
Ocala Eye Retina Consultants, Ocala
Southeastern Retina Associates, PC, Kingsport
Southeastern Retina Associates, P.C., Knoxville
Paducah Retinal Center, Paducah
OSU Eye Physicians and Surgeons, LLC., Columbus
Case Western Reserve University, Cleveland
Retina Associates of Cleveland, Inc., Beachwood
Raj K. Maturi, M.D., P.C., Indianapolis
John-Kenyon American Eye Institute, New Albany
Henry Ford Health System, Dept of Ophthalmology and Eye Care Services, Detroit
Retina Vitrous Center, Grand Blanc
Retina Specialists of Michigan, Grand Rapids
Vitreo-Retinal Associates, Grand Rapids
Wolfe Eye Clinic, West Des Moines
Medical Associates Clinic, P.C., Dubuque
Medical College of Wiconsin, Milwaukee
University of Wisconsin-Madison, Dept of Ophthalmology/Retina Service, Madison
Retina Center, PA, Minneapolis
Mayo Clinic Department of Ophthalmology, Rochester
NorthShore University HealthSystem, Glenview
Northwestern Medical Faculty Foundation, Chicago
University of Illinois at Chicago Medical Center, Chicago
Barnes Retina Institute, St Louis
Retina Associates, P.A., Shawnee Mission
Retina Vitreous Center, Edmond
Dean A. McGee Eye Institute, Oklahoma City
Retina and Vitreous of Texas, Houston
Baylor Eye Physicians and Surgeons, Houston
Retina Consultants of Houston, PA, Houston
Retinal Consultants of San Antonio, San Antonio
Valley Retina Institute, McAllen
Austin Retina Associates, Austin
Retina Research Center, Austin
Southwest Retina Specialists, Amarillo
Texas Retina Associates, Lubbock
Retina Associates of Utah, P.C., Salt Lake City
Retina Associates, Tucson
Eye Associates of New Mexico, Albuquerque
Retina-Vitreous Associates Medical Group, Beverly Hills
Retinal Consultants of Southern California Medical Group, Inc., Westlake Village
Southern California Desert Retina Consultants, MC, Palm Desert
Loma Linda University Health Care, Dept. of Ophthalmology, Loma Linda
California Retina Consultants, Santa Barbara
Bay Area Retina Associates, Walnut Creek
Retina Consultants of Hawaii, Inc., Honolulu
Retina Northwest, PC, Portland
Casey Eye Institute, Portland
University of Washington Medical Center, Seattle
Spokane Eye Clinic, Spokane
University of New Mexico Health Sciences Center, Albuquerque
New England Retina Associates, Norwich
Retina and Vitreous Associates of Kentucky, Lexington
Wilmer Eye Institute at Johns Hopkins, Baltimore
Ophthalmic Consultants of Boston, Boston
Joslin Diabetes Center, Boston
Vitreo-Retinal Associates, PC, Worcester
Eyesight Ophthalmic Services, PA, Portsmouth
The Institute of Ophthalmology and Visual Science (IOVS), Newark
Montefiore Medical Center, The Bronx
University of North Carolina, Chapel Hill
Family Eye Group, Lancaster
Lead Sponsor
Collaborators (1)
National Eye Institute (NEI)
NIH
Genentech, Inc.
INDUSTRY
Regeneron Pharmaceuticals
INDUSTRY
Jaeb Center for Health Research
OTHER