Phase 1/2 Study of X-396, an Oral ALK Inhibitor, in Patients With ALK-positive Non-Small Cell Lung Cancer

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

131

Participants

Timeline

Start Date

June 30, 2012

Primary Completion Date

September 17, 2020

Study Completion Date

September 17, 2020

Conditions
Advanced Solid TumorsNon-small Cell Lung Cancer
Interventions
DRUG

Phase I: X-396 (ensartinib)

Oral, ALK inhibitor

DRUG

Phase II: X-396 (ensartinib)

Expanded Cohort

Trial Locations (14)

10016

New York University Langone Medical Center, New York

20889

Walter Reed National Military Medical Center, Bethesda

33612

Moffitt Cancer Center, Tampa

37203

Tennessee Oncology, PLLC, Nashville

37240

Vanderbilt University, Nashville

53792

University of Wisconsin Carbone Cancer Ctr, Madison

63110

Washington University School of Medicine, St Louis

77030

University of Texas MD Anderson Cancer Center, Houston

90033

University of Southern California Norris Comprehensive Cancer Center, Los Angeles

91010

City of Hope National Med Ctr, Duarte

92093

UCSD Moores Cancer Center, La Jolla

94305

Stanford University, Stanford

97213

Providence Portland Medical Center, Portland

02215

Dana Farber Cancer Institute, Boston

All Listed Sponsors
lead

Xcovery Holdings, Inc.

INDUSTRY

NCT01625234 - Phase 1/2 Study of X-396, an Oral ALK Inhibitor, in Patients With ALK-positive Non-Small Cell Lung Cancer | Biotech Hunter | Biotech Hunter