5
Participants
Start Date
August 31, 2007
Primary Completion Date
May 31, 2015
Study Completion Date
May 31, 2015
Therapeutic Hypothermia
After obtaining written consent, patients are cooled to 33.5°C (+/- 1°C ) for 72 hours and and then rewarmed by 0.5°C per every 3 hours over 18 hours.
Standard of Care Therapy
Patients with hyperammonemia and encephalopathy requiring renal replacement therapy due to a urea cycle disorder or organic acidemia that were treated at Children's National Medical Center over the past 10 years.
Columbia University, Morgan Stanley Children's Hospital, New York
Children's National Medical Center, Washington D.C.
Medical College Wisconsin, Milwaukee
Collaborators (1)
Children's National Research Institute
OTHER
Medical College of Wisconsin
OTHER
Uta Lichter-Konecki
OTHER