Bupropion SR Plus Counseling for Smoking Cessation

PHASE4CompletedINTERVENTIONAL
Enrollment

463

Participants

Timeline

Start Date

January 31, 2001

Primary Completion Date

October 31, 2002

Study Completion Date

October 31, 2003

Conditions
Tobacco DependenceSmoking
Interventions
DRUG

Active bupropion + counseling

"Medications-Pre-quit: 150 mg bupropion per day 7 days before quit attempt, then 150 mg twice daily for 4 days before quit attempt; then 150 mg bupropion twice daily for eight weeks.~Counseling-Pre-quit: two 10 minutes sessions before quit date; eight 10-minute sessions post quit date."

DRUG

Active bupropion, No counseling

"Medication - 150 mg bupropion per day starting week before quit day, then 150 mg twice daily 3 days before quit day, then 150 mg twice daily for eight weeks after quit day.~Counseling: No cessation counseling, only medication checks"

DRUG

Placebo medication + counseling

"Placebo bupropion once daily 7 days before quit day, then twice daily 4 days before quit attempt, then twice daily for 8 weeks after quit day.~Counseling: Two 10-minutes sessions before quit day, then eight 10-minutes sessions for eight weeks after quit day."

DRUG

Placebo medication, No counseling

"Pre-quit: Placebo medication once daily 7 days before quit day, then twice daily before quit day, then twice daily for 8 weeks after quit day.~Counseling: No counseling, just medication checks"

Trial Locations (1)

53711

UW Center for Tobacco Research and Intervention, Madison

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

collaborator

National Institute on Drug Abuse (NIDA)

NIH

lead

University of Wisconsin, Madison

OTHER

NCT01621009 - Bupropion SR Plus Counseling for Smoking Cessation | Biotech Hunter | Biotech Hunter