Pre-Operative Radiation and Veliparib for Breast Cancer

PHASE1CompletedINTERVENTIONAL
Enrollment

19

Participants

Timeline

Start Date

July 22, 2013

Primary Completion Date

September 6, 2023

Study Completion Date

October 17, 2023

Conditions
Breast Cancer
Interventions
RADIATION

Radiation

Patients will receive radiation therapy at a dose of 2.35 Gy per fraction to the breast and regional nodal region for 16 fractions to a total dose of 37.5 Gy. Treatments will be given Monday through Friday. Radiation therapy will start on day 1 of Veliparib.

PROCEDURE

Lumpectomy/Mastectomy

Resection of breast cancer.

DRUG

Veliparib

Pills to be taken twice a day during radiation and for one week after completion of radiation for a total of 29 days.

Trial Locations (6)

46032

IU Schwarz Cancer Center, Carmel

46123

I U Health West, Avon

46202

Indiana University Health Hospital, Indianapolis

Indiana University Health Melvin and Bren Simon Cancer Center, Indianapolis

Indiana University Health Methodist Hospital, Indianapolis

Sidney and Lois Eskenazi Hospital, Indianapolis

All Listed Sponsors
lead

Richard Zellars

OTHER

NCT01618357 - Pre-Operative Radiation and Veliparib for Breast Cancer | Biotech Hunter | Biotech Hunter