26
Participants
Start Date
May 31, 2012
Primary Completion Date
January 31, 2013
Study Completion Date
January 31, 2013
Metformin
metformin 500 mg three times a day, for 3 days
Pretreatment with metformin in combination of infusion of caffeine.
Pretreatment with metformin 500 mg three times a day for 3 days, in combination with pretreatment with caffeine (4 mg/kg intravenously over 10 minutes) prior to FMD measurement
No pretreatment with metformin in combination with infusion of caffeine
No pretreatment with metformin in combination with pretreatment with caffeine (4 mg/kg intravenously over 10 minutes).
Radboud University Nijmegen Medical Centre, Nijmegen
Radboud University Medical Center
OTHER