A Phase II Study of the Safety and Efficacy of MPSK3169A in Patients With Coronary Heart Disease or High Risk of Coronary Heart Disease

PHASE2CompletedINTERVENTIONAL
Enrollment

248

Participants

Timeline

Start Date

May 31, 2012

Primary Completion Date

May 31, 2013

Study Completion Date

July 31, 2013

Conditions
Coronary Heart Disease
Interventions
DRUG

MPSK3169A

Dose regimen A, repeating subcutaneous injections every 4 weeks

DRUG

MPSK3169A

Dose regimen E, repeating subcutaneous injections every 4 weeks

DRUG

MPSK3169A

Dose regimen D, repeating subcutaneous injections every 4 weeks

DRUG

MPSK3169A

Dose regimen C, repeating subcutaneous injections every 4 weeks

DRUG

MPSK3169A

Dose regimen B, repeating subcutaneous injections every 4 weeks

DRUG

Placebo

Repeating subcutaneous injections of placebo every 4 weeks

Trial Locations (73)

1001

Auckland

2317

Hamar

2401

Elverum

2921

Komárom

3110

Tauranga

4313

Sandnes

4400

Nyíregyháza

7001

Nelson

7130

Cape Town

7505

Cape Town

8011

Christchurch

8800

Nagykanizsa

9400

Sopron

13125

Berlin

14609

Rochester

20817

Bethesda

21209

Baltimore

23294

Richmond

27912

Knoxville

28401

Wilmington

29303

Spartanburg

29464

Mt. Pleasant

29650

Greer

32081

Ponte Verde

32216

Jacksonville

37620

Bristol

45212

Cincinnati

45219

Cincinnati

45246

Springdale

46260

Indianapolis

50601

Jičícin

50937

Cologne

52242

Iowa City

57701

Rapid City

58103

Fargo

63110

St Louis

73103

Oklahoma City

74136

Tulsa

75230

Dallas

75231

Dallas

77030

Houston

78006

Boerne

83704

Boise

85395

Goodyear

91978

Spring Valley

92595

Wildomar

94598

Walnut Creek

95608

Carmichael

98801

Wenatchee

04210

Auburn

A1N 1W7

Mount Pearl

A1A 3R5

St. John's

N7T 4X3

Sarnia

M9V 4B4

Toronto

N4S 5P5

Woodstock

H1T 1C8

Montreal

H2P 2M1

Montreal

J7Z 5T3

Saint-Jérôme

G1V 4G2

Sainte-Foy

G8T 7A1

Trois-Rivières

695 01

Hodonín

353 01

Mariánské Lázně

708 52

Ostrava - Poruba

269 01

Rakovník

Unknown

Auckland

0027

Oslo

0160

Oslo

08501

Bardejov

841 07

Bratislava

080 01

Prešov

979 01

Rimavská Sobota

0157

Centurion

0181

Pretoria

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Genentech, Inc.

INDUSTRY