51
Participants
Start Date
October 31, 2012
Primary Completion Date
June 30, 2013
Study Completion Date
June 30, 2013
AZD3241 300 mg BID
The following dose escalation schedule will be used for 300 mg BID: 100 mg BID from Day 1 through Day 7. On Day 8, the patients will start maintenance treatment of 300 mg BID for the duration of the treatment period.
AZD3241 600 mg BID
The following dose escalation schedule will be used for 600 mg BID: 100 mg BID from Day 1 through Day 7 and 300 mg BID from Day 8 through Day 14. On Day 15, the patients will start maintenance treatment of 600 mg BID for the duration of the treatment period.
Placebo
Placebo to AZD3241 BID
Research Site, Birmingham
Research Site, Long Beach
Research Site, New Haven
Research Site, Atlantis
Research Site, Boca Raton
Research Site, Orlando
Research Site, Sunrise
Research Site, Tampa
Research Site, Kansas City
Research Site, Bingham Farms
Research Site, Omaha
Research Site, Lawrenceville
Research Site, Marlton
Lead Sponsor
AstraZeneca
INDUSTRY