A Trial Investigating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of NNC0148-0000-0362 in Healthy Subjects

PHASE1CompletedINTERVENTIONAL
Enrollment

83

Participants

Timeline

Start Date

May 31, 2012

Primary Completion Date

October 31, 2012

Study Completion Date

October 31, 2012

Conditions
DiabetesDiabetes Mellitus, Type 2Healthy
Interventions
DRUG

NNC 0148-0000-0362

Subjects will be randomised to receive a single dose of NNC 0148-0000-0362 orally within each dose group

DRUG

insulin glargine

As an active comparator, one standard dose will be given subcutaneously (s.c., under the skin) within each dose group

DRUG

placebo

Subjects will receive a single dose of oral placebo within each dose group

DRUG

NNC 0148-0000-0362

Single low dose administered orally in randomised order on three dosing visits separated by a wash-out period

DRUG

NNC 0148-0000-0362

Single high dose administered i.v. in randomised order on three dosing visits separated by a wash-out period

DRUG

NNC 0148-0000-0362

Single high dose administered orally in randomised order on three dosing visits separated by a wash-out period

Trial Locations (1)

41460

Neuss

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Novo Nordisk A/S

INDUSTRY