1
Participants
Start Date
September 30, 2012
Primary Completion Date
February 28, 2015
Study Completion Date
February 28, 2015
N-carbamylglutamate
"Active NCG \& Standard of Care Chemical Composition: N-carbamyl-L-glutamic acid (NCG) The daily dose will be 100 mg/kg/ day. The doses are to be divided into 2 equal doses and administered orally or enterally by nasogastric or gastrostomy tube (standard of care will prevail when choosing the mode of drug administration).~The tablets must be dispersed in a minimum of 2.5-10 ml of water and ingested immediately or administered by fast push through a syringe via a nasogastric or gastrostomy tube. The suspension has a slightly acidic taste.~This drug will be administered for 7 days after admission or until discharge (whichever is sooner)."
Standard of Care
Standard of Care
The Children's Hospital of Philadelphia, Philadelphia
Children's National Medical Center, Washington D.C.
University Hospitals of Cleveland/Rainbow Babies and Children's Hospital, Cleveland
The Children's Hospital of Colorado, Aurora
University of California Los Angeles, Los Angeles
Lucile Packard Children's Hospital at Stanford, Palo Alto
Children's Hospital Boston, Boston
Collaborators (1)
Children's National Research Institute
OTHER
Boston Children's Hospital
OTHER
University Hospitals Cleveland Medical Center
OTHER
University of California, Los Angeles
OTHER
Children's Hospital of Philadelphia
OTHER
Lucile Packard Children's Hospital
OTHER
University of Colorado, Denver
OTHER
Mendel Tuchman
OTHER