Phase Ib/II Study of PLX 3397 and Eribulin in Patients With Metastatic Breast Cancer

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

67

Participants

Timeline

Start Date

July 12, 2012

Primary Completion Date

July 5, 2017

Study Completion Date

July 5, 2019

Conditions
Metastatic Breast Cancer
Interventions
DRUG

PLX3397

Dosage Form: 100 mg or 200 mg capsules, Dosage: 400 - 1000 mg, oral administration

DRUG

Eribulin

Dosage Form: 1 mg per 2 mL (0.5 mg per mL); Solution (clear, colorless, sterile, packaged in glass vial) Dosage: 1.4 mg/m2, 2-5 min IV, Day 1, 8 q21 days

Trial Locations (3)

27710

Duke University Cancer Center, Durham

37232

Vanderbilt-Ingram Cancer Center, Nashville

94143

University of California, San Francisco, San Francisco

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Susan G. Komen Breast Cancer Foundation

OTHER

collaborator

Plexxikon

INDUSTRY

lead

Hope Rugo, MD

OTHER

NCT01596751 - Phase Ib/II Study of PLX 3397 and Eribulin in Patients With Metastatic Breast Cancer | Biotech Hunter | Biotech Hunter