Efficacy and Effectiveness of PegInterferon and Ribavirin in Korean Patients With Chronic Hepatitis C

PHASE4CompletedINTERVENTIONAL
Enrollment

272

Participants

Timeline

Start Date

June 30, 2003

Primary Completion Date

December 31, 2011

Study Completion Date

May 31, 2012

Conditions
Chronic Hepatitis C
Interventions
DRUG

Peginterferon alfa-2a plus ribavirin for HCV genotype 1

Patients with genotype 1: treatment with peginterferon α-2a (Roche, Basel, Switzerland) 180 μg/week and daily ribavirin dose of 1,000 mg (for patients with body weight \<75kg) or 1,200 mg (for patients with body weight ≥75kg) for 48 weeks.

DRUG

Peginterferon alfa-2a plus ribavirin for HCV genotype 2/3

Patients with genotype 2 or 3: treatment with peginterferon α-2a 180 μg/week and daily ribavirin dose of 800 mg for 24 weeks.

Trial Locations (1)

138-736

Asan Medical Center, Seoul

Sponsors
All Listed Sponsors
collaborator

Samsung Medical Center

OTHER

collaborator

Severance Hospital

OTHER

collaborator

Gangnam Severance Hospital

OTHER

collaborator

Seoul St. Mary's Hospital

OTHER

collaborator

Korea University Guro Hospital

OTHER

lead

Asan Medical Center

OTHER