Tranexamic Acid for Unilateral Total Knee Arthroplasty

PHASE3CompletedINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

February 29, 2012

Primary Completion Date

October 31, 2012

Study Completion Date

October 31, 2012

Conditions
Blood Loss
Interventions
DRUG

Tranexamic Acid

"Two dosage during the surgical intervention: the first dosage 15-30' before the leg ischemia and the second dosage at 60 -90' after the first dosage.~Each dosage: 2 ampoules of 500mg/5 mL/ampoule"

DRUG

Tranexamic Acid

One dose before the closure of the knee joint: a solution containing 1g of tranexamic acid in 50 ml of normal saline (0.9% sodium chloride) applied with a syringe diffuser.

OTHER

haemostasia

The surgical habitual haemostasia: electrocoagulation of the bleeding tissues

Trial Locations (2)

08024

Hospital de la Esperanza, Barcelona

08025

Hospital de la Santa Creu i Sant Pau, Barcelona

All Listed Sponsors
lead

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

OTHER

NCT01594671 - Tranexamic Acid for Unilateral Total Knee Arthroplasty | Biotech Hunter | Biotech Hunter