Resveratrol-Leucine Metabolite Synergy in Pre-diabetes

NACompletedINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

February 29, 2012

Primary Completion Date

June 30, 2013

Study Completion Date

June 30, 2013

Conditions
Impaired Glucose Tolerance
Interventions
DIETARY_SUPPLEMENT

Resveratrol

A blend of low dose resveratrol and either leucine or HMB will be useful nutraceutical strategies for the control of elevated blood glucose in non-diabetic individuals with elevated fasting glucose. The proposed project is designed to evaluate this hypothesis by comparing the effects of resveratrol (50 mg)/leucine (1.11 g) administered twice daily (bid).

DIETARY_SUPPLEMENT

resveratrol /HMB

resveratrol (50 mg)/HMB (500 mg) twice daily (bid) with placebo on fasting blood glucose, glucose tolerance, insulin, C-peptide, glucagon, fructosamine and F2-isoprostanes in non-diabetic subjects with elevated fasting blood glucose.

OTHER

Placebo treatment

Placebo - one tablet taken twice a day by mouth

Trial Locations (1)

37232

Facility: Vanderbilt University, Nashville

All Listed Sponsors
collaborator

Nutraceutical Discoveries, Inc.

OTHER

lead

Vanderbilt University

OTHER

NCT01593605 - Resveratrol-Leucine Metabolite Synergy in Pre-diabetes | Biotech Hunter | Biotech Hunter