Lactobacillus Reuteri in Management of Helicobacter Pylori Infection in Dyspeptic Patients

NACompletedINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

June 30, 2012

Primary Completion Date

January 31, 2013

Conditions
Helicobacter Pylori Infection
Interventions
DIETARY_SUPPLEMENT

Lactobacillus reuteri

Will receive triple therapy (omeprazole 20 mg b.i.d., amoxicillin 1000 mg b.i.d, clarithromycin 500mg b.i.d) and L. reuteri (is a mixture of L. reuteri DSM 17938 and L. reuteri ATCC PTA 6475, will be delivered a dose of 1x108 CFU each strain, means giving daily chewable tablet containing 2x108 CFU/day) for 2 weeks followed by L. reuteri for another 2 weeks.

DIETARY_SUPPLEMENT

Placebo

Will receive triple therapy (omeprazole 20 mg b.i.d., amoxicillin 1000 mg b.i.d, clarithromycin 500mg b.i.d) and a placebo (1.5 mg per dose as chewable tablets) for 2 weeks followed by placebo for another 2 weeks.

DRUG

Omeprazole

All patients will receive omeprazole 20 mg b.i.d for 2 week

DRUG

Amoxicillin

amoxicillin 1000 mg b.i.d for 2 weeks

DRUG

Clarithromycin

clarithromycin 500mg b.i.d for 2 weeks

Trial Locations (1)

44519

Zagazig University Hospitals, Zagazig

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

BioGaia AB

INDUSTRY

lead

Zagazig University

OTHER_GOV

NCT01593592 - Lactobacillus Reuteri in Management of Helicobacter Pylori Infection in Dyspeptic Patients | Biotech Hunter | Biotech Hunter