NCT01592526View on ClinicalTrials.gov

Autonomic Nervous Activity During the Systemic Inflammatory Response in Trained and Untrained Healthy Volunteers

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

23

Participants

Timeline

Start Date

June 30, 2012

Primary Completion Date

January 31, 2013

Study Completion Date

December 31, 2015

Conditions
Systemic Inflammatory Response Syndrome
Interventions
OTHER

Endotoxin

Bolus injection of LPS 2 ng/kg IV at time = 2 hours (Study day A).

OTHER

Endotoxin + Nicotine

Transdermal application of nicotine patch applied at time = -8 hours (midnight the day before Study day B) + bolus injection of LPS 2 ng/kg at time = 2 hours (Study day 2)

Trial Locations (1)

2100

Center for Inflammation and Metabolism, Rigshospitalet, Copenhagen

All Listed Sponsors
collaborator

Bispebjerg Hospital

OTHER

lead

Rigshospitalet, Denmark

OTHER

NCT01592526 - Autonomic Nervous Activity During the Systemic Inflammatory Response in Trained and Untrained Healthy Volunteers | Biotech Hunter | Biotech Hunter