An Investigational Immuno-Therapy Study to Determine the Safety and Effectiveness of Nivolumab and Daratumumab in Patients With Multiple Myeloma

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

320

Participants

Timeline

Start Date

August 2, 2012

Primary Completion Date

September 25, 2020

Study Completion Date

July 9, 2024

Conditions
Non-Hodgkin's LymphomaHodgkin LymphomaMultiple Myeloma
Interventions
BIOLOGICAL

Nivolumab

Administered by intravenous (IV) infusion

BIOLOGICAL

Ipilimumab

Administered by IV infusion

BIOLOGICAL

Lirilumab

Administered by IV infusion

BIOLOGICAL

Daratumumab

Administered by IV infusion

DRUG

Pomalidomide

Administered PO

DRUG

Dexamethasone

Administered PO and by IV infusion

Trial Locations (43)

9000

Local Institution - 0045, Ghent

9100

Local Institution - 0047, Sint-Niklaas

10065

Local Institution - 0001, New York

Memorial Sloan Kettering Cancer Center, New York

11528

Local Institution - 0039, Athens

19104

Abramson Cancer Center, Philadelphia

Local Institution - 0007, Philadelphia

19111

Fox Chase Cancer Center, Philadelphia

Local Institution - 0004, Philadelphia

21231

Local Institution - 0003, Baltimore

The Sidney Kimmel Comprehensive Cancer Center, Baltimore

32804

Local Institution - 0023, Orlando

40138

Local Institution, Bologna

43210

Local Institution - 0028, Columbus

44000

Local Institution - 0044, Nantes

46202

Local Institution - 0019, Indianapolis

48109

Local Institution - 0011, Ann Arbor

University Of Michigan Health System, Ann Arbor

55905

Local Institution - 0002, Rochester

Mayo Clinic, Rochester

60077

Local Institution - 0037, Skokie

66205

Local Institution - 0018, Westwood

68130

Local Institution - 0033, Omaha

80045

Local Institution - 0017, Aurora

84112

Huntsman Cancer Institute At The Univ. Of Utah, Salt Lake City

Local Institution - 0005, Salt Lake City

86021

Local Institution - 0043, Poitiers

90095

Division Of Hematology & Oncology Ctr. For Health Sciences, Los Angeles

Local Institution - 0012, Los Angeles

93611

Local Institution - 0035, Clovis

97239

Local Institution - 0006, Portland

OHSU Center for Hematologic Malignancies, Portland

06520

Local Institution - 013, New Haven

02215

Dana-Farber Cancer Institute, Boston

Local Institution - 0009, Boston

Local Institution - 0015, Boston

07601

John Theurer Cancer Center, Hackensack

Local Institution - 0014, Hackensack

B-5530

Local Institution, Yvoir

41-500

Local Institution, Chorzów

61-848

Local Institution - 0040, Poznan

02-776

Local Institution - 0049, Warsaw

50-367

Local Institution - 0042, Wroclaw

Sponsors
All Listed Sponsors
collaborator

Janssen, LP

INDUSTRY

lead

Bristol-Myers Squibb

INDUSTRY