Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases in Neurological Disorders in DRC

PHASE3CompletedINTERVENTIONAL
Enrollment

352

Participants

Timeline

Start Date

September 30, 2012

Primary Completion Date

January 31, 2015

Study Completion Date

May 31, 2015

Conditions
Neurological DisordersCerebral MalariaBacterial MeningitisCentral Nervous System TuberculosisNeurosyphilisCryptococcal Meningitis
Interventions
DEVICE

Immunochromatographic HAT tests (DSD)

Immunochromatographic HAT diagnostic tests manufactured by DSD, Korea and FIND

DEVICE

Card Agglutination Trypanosoma Test

Card Agglutination Trypanosoma Test on whole blood and as dilution

DEVICE

TB POC Nucleic Acid Amplification Test (Molbio Diagnostics)

"TB POC Nucleic Acid Amplification Test: microPCR handheld device (Molbio Diagnostics PVT ltd, India)"

DEVICE

TB 3-marker RDT (Tulip diagnostics)

TB 3-marker RDT: ADA2/IFN-g/LAM (Tulip diagnostics, ltd, India) - pending availability for phase 3 validation

DEVICE

Cryptococcal Antigen Lateral Flow Assay (Immy)

Cryptococcal Antigen Lateral Flow Assay (Immy, USA)

Trial Locations (1)

Unknown

Reference Hospital Mosango, Mosango

All Listed Sponsors
collaborator

Institut National de Recherche Biomédicale. Kinshasa, République Démocratique du Congo

OTHER

collaborator

University Hospital, Geneva

OTHER

lead

Institute of Tropical Medicine, Belgium

OTHER

NCT01589289 - Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases in Neurological Disorders in DRC | Biotech Hunter | Biotech Hunter