NCT01582048 - Multicenter Study of Peritransplantation Immunosuppression for Mismatched Hematopoietic Cell Transplantation After Reduced Intensity Conditioning | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

April 30, 2012

Primary Completion Date

August 17, 2016

Study Completion Date

August 17, 2016

Conditions

Patients Receiving Mismatched Allogeneic HCT

Interventions

DRUG

immunosuppression

Conditioning with treosulfan 14 g/m2 day -6 to -4, fludarabine 30 mg/m2/24h day-6 to -2, ATG-Fresenius 20 mg/kg day -4 to -2, rituximab 500 mg/m2 day -1. Unmanipulated PBSC day 0. Postgrafting immunosuppression with mycophenolate mofetil (15 mg/kg TID) and sirolimus (2 mg QD).

Trial Locations (4)

D-55101

Hematology/Oncology Medical Center University Hospital of Mainz, Mainz

D-90419

Bone Marrow Transplantation Unit Medical Center University Hospital of Nuernberg, Nuremberg

D-72076

Department of Hematology/Oncology Medical Center University Hospital of Tuebingen, Tübingen

D-65191

BMT-Unit Deutsche Klinik für Diagnostik, Wiesbaden