Study to Reduce Duration of Antibiotic Therapy in Haematological Patients With Fever and Neutropenia

PHASE4CompletedINTERVENTIONAL
Enrollment

157

Participants

Timeline

Start Date

April 30, 2012

Primary Completion Date

May 31, 2016

Study Completion Date

June 30, 2016

Conditions
Febrile Neutropenia
Interventions
DRUG

Empirical antimicrobial treatment discontinuation

Empirical antimicrobial treatment discontinuation will occur when the patient is: Afebrile, with resolution of signs, symptoms and test abnormalities secondary to complementary source of infection and with normalization of vital signs for ≥ 72 h.

DRUG

Standard empirical antimicrobial treatment discontinuation

"The empirical antimicrobial treatment discontinuation will occur when the patient is:~The neutrophil count is above 500 million per mm3."

Trial Locations (6)

11407

Hospital de Jerez, Jerez de la Frontera

37007

Hospital Clínico Universitario de Salamanca, Salamanca

41013

Virgen del Rocío University Hospital, Seville

08035

Hospital Vall d'Hebron, Barcelona

08036

Hospital Clínic, Barcelona

08907

Bellvitge University Hospital, Barcelona

All Listed Sponsors
lead

Fundación Pública Andaluza para la gestión de la Investigación en Sevilla

OTHER

NCT01581333 - Study to Reduce Duration of Antibiotic Therapy in Haematological Patients With Fever and Neutropenia | Biotech Hunter | Biotech Hunter