Reducing the Burden of Malaria by Targeting Hotspots of Malaria Transmission

NACompletedINTERVENTIONAL
Enrollment

17,506

Participants

Timeline

Start Date

April 30, 2012

Primary Completion Date

November 30, 2012

Study Completion Date

November 30, 2012

Conditions
Malaria
Interventions
DRUG

Artemether-lumefantrine combination

Focal screening and treatment in all households in malaria hotspots prior to the peak transmission season. Screening of a sentinel age group by rapid diagnostic tests; all parasitaemic individuals and household members of parasitaemic individuals will be treated.

BIOLOGICAL

Bacillus thuringiensis

Treatment of all waterbodies within hotspots with Bti or Bs on weekly basis

BIOLOGICAL

Long lasting insecticide treated net (LLINs)

Distribution of LLINs in all households in malaria hotspots; instruction about correct use.

BIOLOGICAL

Indoor Residual Spraying (IRS)

6-monthly IRS with deltamethrin in all households malaria hotspots.

Trial Locations (1)

Unknown

Rachuonyo District

Sponsors
All Listed Sponsors
collaborator

London School of Hygiene and Tropical Medicine

OTHER

collaborator

Kenya Medical Research Institute

OTHER

collaborator

Centers for Disease Control and Prevention

FED

collaborator

International Centre of Insect Physiology and Ecology (ICIPE)

OTHER

collaborator

Division of Malaria Control, Ministry of Health, Nairobi, Kenya

UNKNOWN

lead

Radboud University Medical Center

OTHER