Comparison of Rituximab Induction Therapy Followed by Glatiramer Acetate

PHASE2CompletedINTERVENTIONAL
Enrollment

53

Participants

Timeline

Start Date

February 29, 2012

Primary Completion Date

May 31, 2015

Study Completion Date

May 31, 2015

Conditions
Multiple Sclerosis
Interventions
DRUG

Rituximab

intravenous (IV) infusion of 1000 mg of rituximab on study days 1 (baseline visit) and 15

DRUG

Glatiramer Acetate

20 mg injected subcutaneously daily

OTHER

Placebo

Subjects will receive an intravenous (IV) infusion of 1000 mg of rituximab or placebo (normal saline) on study days 1 (baseline visit) and 15 according to the rituximab infusion protocol. On study day 28, all subjects will initiate standard GA therapy, 20 mg injected subcutaneously daily.

Trial Locations (1)

80045

University of Colorado Hospital, Aurora

All Listed Sponsors
collaborator

Rocky Mountain MS Research Group, LLC

OTHER

lead

University of Colorado, Denver

OTHER

NCT01569451 - Comparison of Rituximab Induction Therapy Followed by Glatiramer Acetate | Biotech Hunter | Biotech Hunter