CT Antigen TCR-redirected T Cells for Ovarian Cancer.

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

9

Participants

Timeline

Start Date

July 9, 2013

Primary Completion Date

June 6, 2017

Study Completion Date

June 6, 2017

Conditions
Ovarian Cancer
Interventions
BIOLOGICAL

NYESO-1c259 T cells

Cytoreductive chemotherapy followed by infusion with NYESO-1(C259) transduced autologous T cells. Patients will receive at least 1x10⁹ transduced cells, however the target dose for this protocol is for patients to receive 5x10⁹ transduced cells with a maximum possible dose of 6x10⁹ administered as a single intravenous (IV) infusion.

Trial Locations (5)

14263

Roswell Park Cancer Institute, Buffalo

33136

University of Miami, Sylvester Comprehensive Cancer Center, Miami

77030

MD Anderson Cancer Center, Houston

91010

City of Hope National Medical Center, Duarte

94305

Stanford Cancer Institute, Stanford

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Adaptimmune

INDUSTRY

NCT01567891 - CT Antigen TCR-redirected T Cells for Ovarian Cancer. | Biotech Hunter | Biotech Hunter