Melatonin Associated to Acid Inhibition for Chemoprevention in Barret Esophagus: a Pilot Study

PHASE3CompletedINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

April 30, 2012

Primary Completion Date

June 30, 2017

Study Completion Date

June 30, 2017

Conditions
Barrett's Esophagus
Interventions
DRUG

Omeprazole

Omeprazole 40 mg/day alone. Patients will take the capsule once in the morning before breakfast. This is the standard therapy for patients suffering from Barrett's esophagus.

DRUG

Melatonin

Omeprazole 40 mg/day + Circadin 6 mg/12 hours. Patients will take the Omeprazole capsule once in the morning before breakfast together with 3 tables of 2 mgs of Circadin (melatonin). In the evening, before dinner, patients will take 3 tablets of 2 mg of Circadin.

Trial Locations (1)

50009

Hospital Clínico Universitario Lozano Blesa, Zaragoza

All Listed Sponsors
lead

Aragon Institute of Health Sciences

OTHER

NCT01566474 - Melatonin Associated to Acid Inhibition for Chemoprevention in Barret Esophagus: a Pilot Study | Biotech Hunter | Biotech Hunter