Effect of Dentifrice Usage Regime on Delivery and Efficacy of Fluoride

PHASE4CompletedINTERVENTIONAL
Enrollment

65

Participants

Timeline

Start Date

January 1, 2009

Primary Completion Date

June 1, 2009

Study Completion Date

June 1, 2009

Conditions
Dental Caries
Interventions
DRUG

Sodium fluoride / silica and carbopol, 0.5g

Dentifrice containing 1150 parts per million (ppm) fluoride as sodium fluoride / silica and 0.4% carbopol

DRUG

Sodium fluoride / silica and carbopol, 1.5g

Dentifrice containing 1150 ppm fluoride as sodium fluoride / silica and 0.4% carbopol

DRUG

Sodium fluoride / silica and carbopol, 1.5g

Dentifrice containing 250 ppm fluoride as sodium fluoride / silica and 0.4% carbopol

OTHER

Fluoride free dentifrice

A non fluoride dentifrice was given to participants of each arm at washout period

Trial Locations (1)

46202

Indiana University School of Dentistry, Indianapolis

Sponsors

Lead Sponsor

All Listed Sponsors
lead

GlaxoSmithKline

INDUSTRY