NCT01562132View on ClinicalTrials.gov

Safety Study of Fluconazole in Combination With Flucytosine for the Treatment of Early Cryptococcal Infection

PHASE2TerminatedINTERVENTIONAL
Enrollment

6

Participants

Timeline

Start Date

September 30, 2013

Primary Completion Date

July 31, 2014

Study Completion Date

July 31, 2014

Conditions
Cryptococcal Infection Disseminated
Interventions
DRUG

Flucytosine and fluconazole

Flucytosine 100mg/kg/day in 4 divided doses orally for 14 days given in combination with fluconazole 1200mg orally once daily for 14 days, followed by 800mg orally once daily for 8 weeks, followed by 200mg orally once daily

DRUG

Fluconazole

fluconazole 1200mg orally once daily for 14 days, followed by 800mg orally once daily for 8 weeks, followed by 200mg orally once daily

Trial Locations (2)

Unknown

Family AIDS Care and Education Services, Kisumu

Family AIDS Care and Education Services, Sindo

Sponsors
All Listed Sponsors
collaborator

National Institute of Neurological Disorders and Stroke (NINDS)

NIH

collaborator

Kenya Medical Research Institute

OTHER

collaborator

Bausch Health Americas, Inc.

INDUSTRY

collaborator

University of Nairobi

OTHER

lead

Yale University

OTHER