Brain Imaging, Cognitive Enhancement and Early Schizophrenia

NACompletedINTERVENTIONAL
Enrollment

102

Participants

Timeline

Start Date

June 30, 2012

Primary Completion Date

June 30, 2018

Study Completion Date

June 30, 2018

Conditions
SchizophreniaSchizoaffective Disorder
Interventions
BEHAVIORAL

Cognitive Enhancement Therapy

Cognitive Enhancement Therapy (CET) consists of approximately 60 hours of computer-assisted neurocognitive training in attention, memory, and problem-solving; and 45 social-cognitive group sessions that employ in vivo learning experiences to foster the development of social wisdom and success in interpersonal interactions. CET begins with 3 months of weekly 1-hour neurocognitive training in attention, after which patients begin the weekly 1.5-hour social-cognitive groups. Neurocognitive training then proceeds concurrently with the socialcognitive groups.

BEHAVIORAL

Enriched Supportive Therapy

"Enriched Supportive Therapy is an individual approach that includes the established principles of supportive therapy previously tested by our group, which are enriched by selected practice principles from the effective Personal Therapy. These manualized supportive therapeutic practices include active listening, correct empathy, appropriate reassurance, basic psychoeducation, including computer-based educational programs, reinforcement of health-promoting initiatives, the provision of case management, and reliance on the advocacy and advice of the therapist in times of crisis."

Trial Locations (5)

15213

University of Pittsburgh, Pittsburgh

Western Psychiatry Institute and Clinic, Pittsburgh

02215

Beth Israel Deaconess Medical Center, Boston

02139

Massachusetts Institute of Technology, Cambridge

02129

Massachusetts General Hospital, Charlestown

All Listed Sponsors
collaborator

University of Pittsburgh

OTHER

collaborator

Massachusetts General Hospital

OTHER

collaborator

National Institute of Mental Health (NIMH)

NIH

lead

Beth Israel Deaconess Medical Center

OTHER

NCT01561859 - Brain Imaging, Cognitive Enhancement and Early Schizophrenia | Biotech Hunter | Biotech Hunter