194
Participants
Start Date
October 31, 2012
Primary Completion Date
December 31, 2015
Study Completion Date
March 31, 2017
Continuous tissue perfusion monitoring by near-infrared spectroscopy (NIRS) and intramuscular pressure (IMP)
Continuous monitoring of tissue perfusion using NIRS in all 4 leg muscle compartments and IMP via indwelling catheters in anterior and deep posterior compartments. These measures will not provided in real time to treating physicians. All clinical care, including the diagnosis of ACS, will be according to the current standard-of-care practiced at each institution, Clinicians may use the indwelling IMP monitor to obtain up to 2 discrete measures of IMP if they encounter a clinical situation in which they would normally measure IMP as an adjunct in their normal standard-of-care for the monitoring and diagnosis of compartment syndrome. Patients who undergo fasciotomy will also have NIRS and IMP values recorded from all 4 leg compartments immediately before and after fasciotomy.
Wake Forest University Baptist Medical Center, Winston-Salem
Carolinas Medical Center, Charlotte
Vanderbilt Medical Center, Nashville
Hennepin County Medical Center / Regions Hospita, Minneapolis
San Antonio Military Medical Center, Fort Sam Houston
Denver Health and Hospital Authority, Denver
University of Maryland/R Adams Cowley Shock Trauma Medical Center, Baltimore
Major Extremity Trauma Research Consortium
OTHER