Predicting Acute Compartment Syndrome (PACS)

NACompletedINTERVENTIONAL
Enrollment

194

Participants

Timeline

Start Date

October 31, 2012

Primary Completion Date

December 31, 2015

Study Completion Date

March 31, 2017

Conditions
Acute Compartment Syndrome
Interventions
OTHER

Continuous tissue perfusion monitoring by near-infrared spectroscopy (NIRS) and intramuscular pressure (IMP)

Continuous monitoring of tissue perfusion using NIRS in all 4 leg muscle compartments and IMP via indwelling catheters in anterior and deep posterior compartments. These measures will not provided in real time to treating physicians. All clinical care, including the diagnosis of ACS, will be according to the current standard-of-care practiced at each institution, Clinicians may use the indwelling IMP monitor to obtain up to 2 discrete measures of IMP if they encounter a clinical situation in which they would normally measure IMP as an adjunct in their normal standard-of-care for the monitoring and diagnosis of compartment syndrome. Patients who undergo fasciotomy will also have NIRS and IMP values recorded from all 4 leg compartments immediately before and after fasciotomy.

Trial Locations (7)

27157

Wake Forest University Baptist Medical Center, Winston-Salem

28204

Carolinas Medical Center, Charlotte

37232

Vanderbilt Medical Center, Nashville

55415

Hennepin County Medical Center / Regions Hospita, Minneapolis

78234

San Antonio Military Medical Center, Fort Sam Houston

80203

Denver Health and Hospital Authority, Denver

212101

University of Maryland/R Adams Cowley Shock Trauma Medical Center, Baltimore

All Listed Sponsors
lead

Major Extremity Trauma Research Consortium

OTHER

NCT01561261 - Predicting Acute Compartment Syndrome (PACS) | Biotech Hunter | Biotech Hunter