201
Participants
Start Date
September 30, 2011
Primary Completion Date
December 31, 2015
Study Completion Date
September 30, 2016
Preconditioning
Blood pressure cuff inflated to 200 mmHg in the upper extremity for 5 minutes to cause forearm ischemia by external compression of the brachial artery. This will be followed by 5 minutes of cuff deflation to allow for preperfusion. The ischemia-reperfusion cycle will be repeated 3 times for a total duration of 30 minutes, equally divided between ischemia and reperfusion.
Control
Blood pressure cuff inflated to 40-50 mmHg in the upper extremity
Minneapolis VA Health Care System, Minneapolis, MN, Minneapolis
VA Office of Research and Development
FED