9,449
Participants
Start Date
May 31, 2012
Primary Completion Date
April 30, 2016
Study Completion Date
April 30, 2018
POC CD4 and Peer Case Management
HIV-positives will receive prevention with positives (PwP) counseling and point of care CD4 counts. Those with CD4 \<500/μL will be assigned a peer case manager to link the person to ART at study-participating HIV clinics, support ART and PwP adherence and care retention.
HCV+PWID
Deliver direct acting antiviral (DAA) regimens for HCV+PWID. We will treat both active and inactive confirmed HCV viremic PWID from either Medication Assisted Treatment (MAT) clinics in Nairobi, Mombasa, and Malindi, Kenya or Collaborating partners' sites/Drop-in Centers (DICs) in Mombasa and Mtwapa, Kenya with direct acting antiviral (DAA) regimens. The mode of treatment delivery will be Directly Observed Therapy (DOT) for 84 consecutive doses (one dose per day). All participants will receive pre, post and ongoing counseling as per study protocol.
Control - No intervention
National AIDS/STD Control Programme (NASCOP), Nairobi
NYU Langone Health
OTHER
Kenya National AIDS & STI Control Programme
OTHER
National Institute on Drug Abuse (NIDA)
NIH
Yale University
OTHER