NCT01557712View on ClinicalTrials.gov

Estimate the Efficiency of the Association of an Injection of Ketamine and the Venlafaxine in the Severe Major Depressive Disorder for Six Weeks

PHASE3CompletedINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

March 31, 2012

Primary Completion Date

January 31, 2017

Study Completion Date

January 31, 2017

Conditions
Major Depressive Disorder
Interventions
DRUG

ketamine venlafaxine

"After a washout period of 7 days of psychotropic medications with the exception of cyamemazine and hydroxyzine:~* Intravenous injection on day 0 to 0.5 mg / kg of ketamine~* D0 to D4: 75 mg of venlafaxine~* D4 to D14: 150 mg per day of venlafaxine~* D14 to D42: 150 mg daily of venlafaxine to 375 mg per day of venlafaxine if patient not responder"

DRUG

Venlafaxine

"After a washout period of 7 days of psychotropic medications with the exception of cyamemazine and hydroxyzine:~* Intravenous injection on day 0 to 0.5 mg / kg of placebo (saline serum)~* D0 to D4: 75 mg of venlafaxine~* D4 to D14: 150 mg per day of venlafaxine~* D14 to D42: 150 mg daily of venlafaxine to 375 mg per day of venlafaxine if patient not responder"

Trial Locations (1)

38000

Centre hospitalier universitaire, Grenoble

All Listed Sponsors
lead

University Hospital, Grenoble

OTHER

NCT01557712 - Estimate the Efficiency of the Association of an Injection of Ketamine and the Venlafaxine in the Severe Major Depressive Disorder for Six Weeks | Biotech Hunter | Biotech Hunter