Cytotoxic T-Lymphocytes for EBV-positive Lymphoma, GRALE

PHASE1RecruitingINTERVENTIONAL
Enrollment

136

Participants

Timeline

Start Date

January 14, 2013

Primary Completion Date

March 1, 2027

Study Completion Date

July 1, 2027

Conditions
Hodgkin's DiseaseNon-Hodgkin's LymphomaLymphoproliferative DiseaseLymphoma
Interventions
BIOLOGICAL

EBV-specific T cells: A

Patients may receive cells with or without lymphodepletion. Dose Level 3: 1 x 10\^8 cells/m2 + 2 x 10\^8 cells/m2

BIOLOGICAL

EBV-specific T cells: B

Patients may receive cells with or without lymphodepletion. Dose Level 3: 1 x 10\^8 cells/m2 + 2 x 10\^8 cells/m2

Trial Locations (3)

77030

NOT_YET_RECRUITING

Harris Health System (includes ben Taub General Hospital and Smith), Houston

RECRUITING

Houston Methodist Hospital, Houston

RECRUITING

Texas Children's Hospital, Houston

All Listed Sponsors
collaborator

The Methodist Hospital Research Institute

OTHER

collaborator

Center for Cell and Gene Therapy, Baylor College of Medicine

OTHER

collaborator

National Institutes of Health (NIH)

NIH

collaborator

National Cancer Institute (NCI)

NIH

collaborator

Harris County Hospital District

OTHER_GOV

lead

Baylor College of Medicine

OTHER