36
Participants
Start Date
February 8, 2012
Primary Completion Date
April 20, 2017
Study Completion Date
July 1, 2018
AMG 386
AMG 386 dose will be calculated using the subjects actual body weight (Kg). Supplied in 240 mg v will be administered as an intravenous (IV) infusion using an intravenous infusion pump given over a 60-minute period.
Abiraterone
A 1,000 mg dose of abiraterone should be taken orally once daily
Prednisone
Prednisone should be taken orally either, at 5mg twice a day for each dose or 10 mg once a day a patients preference.
Fox Chase Cancer Center, Philadelphia
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda
National Cancer Institute (NCI)
NIH