Effectiveness of Vyvanse Compared to Concerta in Adolescents With Attention-deficit/Hyperactivity Disorder

PHASE4CompletedINTERVENTIONAL
Enrollment

464

Participants

Timeline

Start Date

April 17, 2012

Primary Completion Date

January 22, 2014

Study Completion Date

January 22, 2014

Conditions
Attention-deficit/Hyperactivity Disorder
Interventions
DRUG

Lisdexamfetamine dimesylate

Daily oral dosing in the AM of optimized dose, ranging from 30- 70 mg. 5 week dose optimization, 3 week dose maintenance

DRUG

Methylphenidate Hydrochloride

Daily oral dosing in the AM of optimized dose, ranging from 18-72 mg. 5 week dose optimization, 3 week dose maintenance

DRUG

Placebo

Daily oral dosing in the AM for 8 weeks

Trial Locations (79)

10029

Mount Sinai School of Medicine, New York

20170

NeuroScience, Inc., Herndon

20852

Neuroscientific InSights, Rockville

20882

Marc Hertzman MD, PC, Rockville

22903

University of Virginia Child and Family Psychiatry Clinical, Charlottesville

27705

Duke Child and Family Study Center, Durham

29407

Carolina Clinical Trials, Inc., Charleston

29464

Coastal Carolina Research Center, Mt. Pleasant

30328

Atlanta Institute of Medicine and Research, Atlanta

32256

Clinical Neuroscience Solutions, Inc., Jacksonville

32608

Sarkis Clinical Trials, Gainesville

32751

Florida Clinical Research Center, LLC, Maitland

32806

Clinical Neuroscience Solutions, Inc., Orlando

Compass Research, LLC, Orlando

33013

Amedica Research Institute, Hialeah

33161

Scientific Clinical Research, Inc., Miami

33319

Fidelity Clinical Research, Inc., Lauderhill

33407

Janus Center for Psychiatric Research, West Palm Beach

33613

Stedman Clinical Trials, Tampa

34201

Florida Clinical Research Center, LLC, Bradenton

38119

Research Strategies of Memphis, LLC, Memphis

39232

Precise Research Centers, Flowood

40509

University of Kentucky, Lexington

42003

Four Rivers Clinical Research, Paducah

43210

The Ohio State University Nisonger Center, Columbus

44122

North Coast Clinical Trials, Beachwood

44195

Cleveland Clinic, Cleveland

44281

Family Practice of Wadsworth, Inc., Wadsworth

45040

Professional Psychiatric Services, Mason

45219

University of Cincinnati Dept. of Psychiatry & Behavioral, Cincinnati

45417

Midwest Clinical Research Center, Dayton

48083

Behavioral Medical Center - Troy, Troy

48307

Rochester Center for Behavioral Medicine, Rochester Hills

48314

Clinical Neurophysiology Services, PC, Sterling Heights

58103

Innovis Health, LLC, Fargo

60048

Capstone Clinical Research, Libertyville

60301

Neuroscience Research Institute, Inc, Oak Park

60453

Advocate Hope Children's Hospital, Oak Lawn

60523

American Medical Research, Inc, Oak Brook

60563

AMR Baber Research Group, Inc., Naperville

AMR Conventions Research, Naperville

63301

St Charles Psychiatric Associates, Saint Charles

64118

Comprehensive Psychiatric Associates, Gladstone

66211

Psychiatric Associates, Overland Park

68105

University of Nebraska Medical Center, Omaha

68526

Premier Psychiatric Research Institute, Lincoln

72211

Clinical Study Centers, LLC, Little Rock

77008

Claghorn-Lesem Reseach Clinic, Ltd., Houston

77081

Texas Center for Drug Development, Inc., Houston

77090

Red Oak Psychiatry Associates, PA, Houston

77488

Wharton Research Center, Inc., Wharton

77586

R/D Clinical Research, Inc., Lake Jackson

78229

Clinical Trials of Texas, Inc., San Antonio

University of Texas HSC at San Antonio Dept. of Psychiatry, San Antonio

78731

FutureSearch Trials, Austin

79423

Westex Clinical Investigations, Lubbock

80910

MCB Clinical Research Centers, LLC, Colorado Springs

84105

Psychiatric & Behavioral Solutions, Salt Lake City

85254

Melmed Center, Scottsdale

89128

Center for Psychiatry and Behavioral Medicine, Inc., Las Vegas

90274

Peninsula Research Associates, Inc., Rolling Hills Estates

91950

Synergy Clinical Research Center, National City

92108

PCSD - Feighner Research, San Diego

92595

Elite Clinical Trials, Wildomar

92701

Neuropsychiatric Research Center of Orange County, Santa Ana

92868

Pacific Clinical Research Medical Group, Orange

SDS Clinical Trials, Inc., Orange

94143

University of California, San Francisco, San Francisco

97030

Cyn3rgy Research, Gresham

97210

Oregon Center for Clinical Investigations, Inc. (OCCI, Inc.), Portland

Summit Research Network (Oregon) Inc., Portland

97301

Oregon Center for Clinical Investigations, Inc., Salem

98007

Northwest Clinical Research Center, Bellevue

98033

Eastside Therapeutic Resource, Kirkland

98104

Summit Research Network (Seattle), LLC, Seattle

99202

Rockwood Clinic, P.S., Spokane

08002

Center for Emotional Fitness, Cherry Hill

08026

CRCNJ - Clinical Research Center of New Jersey, Gibbsboro

07856

Neurcognitive Institute, Mount Arlington

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Shire

INDUSTRY

NCT01552915 - Effectiveness of Vyvanse Compared to Concerta in Adolescents With Attention-deficit/Hyperactivity Disorder | Biotech Hunter | Biotech Hunter