Pharmacokinetic Study of Primaquine and Pyronaridine-Artesunate in Healthy Subjects

PHASE1CompletedINTERVENTIONAL
Enrollment

17

Participants

Timeline

Start Date

May 31, 2012

Primary Completion Date

October 31, 2012

Study Completion Date

October 31, 2012

Conditions
Healthy
Interventions
DRUG

Primaquine and Pyronaridine-artesunate

"Subject will receive primaquine (PQ) then receive pyronaridine-artesunate (PA)after 1 week washout period and receive PQ together with PA for the third regimen after 8 weeks washout period~Primaquine:~\- Dosage: 2 tablets~and~Pyronaridine-Artesunate:~\- Dosage: 3 tablets"

DRUG

Primaquine and Pyronaridine-Artesunate

"Subject will receive primaquine (PQ) then receive PQ together dihydroartemisinin-piperaquine (DHA-PQP) after 1 week washout period and receive DHA-PQP for the third regimen after 8 weeks washout period.~Primaquine:~\- Dosage: 2 tablets~and~Pyronaridine-Artesunate:~\- Dosage: 3 tablets"

Trial Locations (1)

10400

Hospital of Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Bangkok

All Listed Sponsors
lead

University of Oxford

OTHER

NCT01552330 - Pharmacokinetic Study of Primaquine and Pyronaridine-Artesunate in Healthy Subjects | Biotech Hunter | Biotech Hunter