220
Participants
Start Date
March 31, 2012
Primary Completion Date
July 31, 2017
Study Completion Date
July 31, 2017
Involved Field Irradiation(IFI)
Involved Field Irradiation(IFI):only irradiate positive lymph node by CT or PET-CT Radiation: IMRT IMRT is administered with chemotherapy from week 1 to week 8PTV-GTV(primary tumor):66-70Gy/33\~35F,once a day, 5 times per week PTV-CTV(Clinical target,primary tumor extended 3cm in Axial):50-56Gy/33\~35f,once a day, 5 times per week PTV-GTVnd(positive node):66-70Gy/33\~35F,once a day, 5 times per week.
docetaxel and cisplatin
Drug: docetaxel and cisplatin.Consists of docetaxel 60-80mg/m2 day 1 and cisplatin 25mg/m2 days 1 to 3, repeat every 3 weeks, for 2 cycles.
Elective Nodal Irradiation (ENI)
The CTVn of ENI included the involved lymph node regions and clinically uninvolved lymph nodal stations according to the location of primary tumor. Lymph node station numbers 1/2/4/5/7, 2/4/5/7 and 4/5/7/16/17were included for upper, middle and lower thoracic ESCC in the ENI arm respectively.
Guangxi Tumor Hospital, Nanning
GuiZhou Cancer Hospital, Guiyang
The Second People's Hospital of Sichuan, Chengdu
Yunnan Tumor Hospital, The Third Affiliated Hospital of KUNMING Medical University, Kunming
Chengya Chou
OTHER