Drug Drug Interaction Study Of Crizotinib With Esomeprazole.

PHASE1CompletedINTERVENTIONAL
Enrollment

16

Participants

Timeline

Start Date

May 31, 2012

Primary Completion Date

May 31, 2012

Study Completion Date

May 31, 2012

Conditions
Healthy
Interventions
DRUG

crizotinib

Each subject in Treatment A will receive a 250 mg single oral dose of crizotinib administered in a fasted state as 1x 250 mg Formulated Capsule on Day 1 and each subject in Treatment B will receive a 250 mg single oral dose of crizotinib administered in a fasted state as 1x 250 mg Formulated Capsule on Day 5

DRUG

esomeprazole

Each subject in Treatment B will receive 40 mg daily dose of esomeprazole from Day 1 to Day 5

Trial Locations (1)

B-1070

Pfizer Investigational Site, Brussels

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY

NCT01549574 - Drug Drug Interaction Study Of Crizotinib With Esomeprazole. | Biotech Hunter | Biotech Hunter