Comparison of Dexmedetomidine and Propofol-Remifentanil Conscious Sedation for Awake Craniotomy for Tumor Surgery

NACompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

November 30, 2012

Primary Completion Date

December 31, 2014

Study Completion Date

December 31, 2014

Conditions
Brain Tumor
Interventions
DRUG

Dexmedetomidine

The infusion begins at dexmedetomidine 0.3-0.4 mcg/kg/hr for 15 min, and then titrated down to 0.1-0.2 mcg/kg/hr.

DRUG

Propofol

The infusion begins at propofol 25-250 mcg/kg/min for 15 min, and then titrated to effect.

DRUG

Remifentanil

The infusion begins at remifentanil 0.01-0.1 mcg/kg/min for 15 min, and then titrated to effect.

Trial Locations (1)

M5T 2S8

UHN Toronto Western Hospital, Toronto

All Listed Sponsors
lead

Nicolai Goettel

OTHER

NCT01545297 - Comparison of Dexmedetomidine and Propofol-Remifentanil Conscious Sedation for Awake Craniotomy for Tumor Surgery | Biotech Hunter | Biotech Hunter