Dose Ranging Study of BMS-945429 in Subjects With Moderate to Severe Crohn's Disease

PHASE2TerminatedINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

June 30, 2012

Primary Completion Date

December 31, 2013

Study Completion Date

December 31, 2013

Conditions
Crohn's Disease
Interventions
BIOLOGICAL

Placebo matching with BMS-945429

Injection, Intravenous (IV), 0 mg, Day One Only, One Day

BIOLOGICAL

Placebo matching with BMS-945429

Injection, Subcutaneous (SC), 0 mg, Every 4 weeks, 8 weeks

BIOLOGICAL

Placebo matching with BMS-945429

Injection, Subcutaneous (SC), 0 mg, Week 4 Only, One Day

BIOLOGICAL

Placebo matching with BMS-945429

Injection, Subcutaneous (SC), 0 mg, Every 4 weeks, Up to 48 weeks

BIOLOGICAL

BMS-945429

Injection, Intravenous (IV), 600 mg, Day One Only, One Day

BIOLOGICAL

BMS-945429

Injection, Subcutaneous (SC), 200 mg, Week 8 only, One Day

BIOLOGICAL

BMS-945429

Injection, Intravenous (IV), 300 mg, Day One Only, One Day

BIOLOGICAL

BMS-945429

Injection, Subcutaneous (SC), 100 mg, Week 8 Only, One Day

BIOLOGICAL

BMS-945429

Injection, Subcutaneous (SC), 400 mg, Day One and Week 4, 4 weeks

BIOLOGICAL

BMS-945429

Injection, Intravenous (IV), 150 mg, Day One Only, One Day

BIOLOGICAL

BMS-945429

Injection, Subcutaneous (SC), 100 mg, Every 4 weeks, Up to 48 weeks

BIOLOGICAL

BMS-945429

Injection, Subcutaneous (SC), 200 mg, Every 4 weeks, Up to 48 weeks

BIOLOGICAL

BMS-945429

Injection, Subcutaneous (SC), 200 mg, Every 4 weeks, Up to 96 weeks, depending on when subject enters this period

Trial Locations (56)

100

Local Institution, Taipei

1090

Local Institution, Vienna

1136

Local Institution, Budapest

4025

Local Institution, Debrecen

7623

Local Institution, Pécs

8091

Local Institution, Zurich

12601

Premier Medical Group Of The Hudson Valley, Pc, Poughkeepsie

14080

Local Institution, Mexico City

20097

Local Institution, San Donato Milanese (mi)

24105

Local Institution, Kiel

32610

University Of Florida, Gainesville

33600

Local Institution, Pessac

35128

Local Institution, Padua

38138

Gastro One, Germantown

39120

Local Institution, Magdeburg

40202

University Of Louisville, Louisville

40237

Local Institution, Düsseldorf

42270

Local Institution, Saint-Priest-en-Jarez

44623

Local Institution, Herne

48155

Local Institution, Münster

50012

Local Institution, Hradec Králové

50134

Local Institution, Florence

59037

Local Institution, Lille

60431

Local Institution, Frankfurt A. M

63003

Local Institution, Clermont-Ferrand

64239

Local Institution, Tel Aviv

64460

Local Institution, Monterrey

71013

Local Institution, San Giovanni Rotondo (fg)

74104

Options Health Research, Llc, Tulsa

76100

Local Institution, Rehovot

80124

South Denver Gastroenterology, Pc, Lone Tree

80756

Local Institution, Kaohsiung City

91031

Local Institution, Jerusalem

92093

University Of California, San Diego, La Jolla

92114

Precision Research Institute, Llc, San Diego

141001

Local Institution, Ludhiana

400020

Local Institution, Mumbai

411030

Local Institution, Pune

500082

Local Institution, Hyderabad

T2N 4Z6

Local Institution, Calgary

V6Z 2K5

Local Institution, Vancouver

S7N 0W8

Local Institution, Saskatoon

06200

Local Institution, Nice

Unknown

Local Institution, Hong Kong

400 029

Local Institution, Mumbai

00152

Local Institution, Roma

6500 HB

Local Institution, Nijmegen

31-864

Local Institution, Krakow

90-302

Local Institution, Lodz

50-556

Local Institution, Wroclaw

53-114

Local Institution, Wroclaw

120-752

Local Institution, Seoul

135-710

Local Institution, Seoul

138-736

Local Institution, Seoul

HU3 2JZ

Local Institution, Hull

HA1 2UJ

Local Institution, Harrow

Sponsors

Lead Sponsor

All Listed Sponsors
lead

CSL Behring

INDUSTRY