NCT01543555View on ClinicalTrials.gov

Lowering the Risk of Operative Complications Using Atorvastatin Loading Dose

PHASE3CompletedINTERVENTIONAL
Enrollment

648

Participants

Timeline

Start Date

November 30, 2012

Primary Completion Date

June 30, 2015

Study Completion Date

June 30, 2015

Conditions
Myocardial InfarctionPeripheral Vascular DiseaseAortic Aneurism
Interventions
DRUG

Atorvastatin

Atorvastatin 80mg anytime within 18 hours before surgery. A postoperative 40mg atorvastatin dose administered at least 12 hours after the 80mg loading dose. Subsequently, 40mg atorvastatin daily for the next seven days.

DRUG

Placebo

Matching placebo 80mg anytime within 18 hours before surgery. A postoperative 40mg matching placebo dose administered at least 12 hours after the 80mg loading dose. Subsequently, 40mg placebo daily for the next seven days.

Trial Locations (1)

04005-000

Hospital do Coração, São Paulo

All Listed Sponsors
lead

Hospital do Coracao

OTHER

NCT01543555 - Lowering the Risk of Operative Complications Using Atorvastatin Loading Dose | Biotech Hunter | Biotech Hunter