Study in Healthy Volunteers to Assess Effect of Omeprazole and Ranitidine on the Pharmacokinetics of Vandetanib

PHASE1CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

February 29, 2012

Primary Completion Date

September 30, 2012

Study Completion Date

September 30, 2012

Conditions

Medullary Thyroid Cancer

Interventions

DRUG

vandetanib

Oral tablets, 300 mg, single dose

DRUG

omeprazole

Oral capsules, 40 mg, multiple doses

DRUG

ranitidine

Oral tables, 150 mg, multiple doses

Trial Locations (1)

Research Site, Overland Park