140
Participants
Start Date
November 30, 2011
Primary Completion Date
December 31, 2014
Study Completion Date
December 31, 2014
Cerebral oxygenation intervention
The protocol for interventions to increase cerebral oxygenation levels above 60% optimizing pH, PaO2, PaCO2, bispectral index, central venous pressure, mean arterial pressure, venous oxygen saturation, and hematocrit. In addition, cerebral perfusion pressure of 70-80 mm Hg and flow \>2.0 l/min/m2 will be maintained during cardiopulmonary bypass. In the ICU, temperatures will be maintained below 38 degrees by administering antipyretics or cooling, and dexmedetomidine will be used if the patient is agitated.
Icahn School of Medicine at Mount Sinai, New York
Icahn School of Medicine at Mount Sinai
OTHER