431
Participants
Start Date
July 10, 2012
Primary Completion Date
April 30, 2018
Study Completion Date
April 30, 2018
Mesalazine
Mesalazine (Pentasa) comes in 500mg capsules, and doses will need to be rounded to the nearest 500mg increment, with a maximum dose of 76 mg/kg/day. The average dose for the pediatric population will be approximately 70 mg/kg/day. Patients will be allowed to escalate to the final dose over 4 days to minimize side-effects such as headache.
IV Corticosteroid
Treatment with IV Corticosteroid
Oral Corticosteroids
Treatment with oral corticosteroids
Additional Therapies
Anti-TNFα, Calcineurin inhibitor, Immunomodulator
Colectomy
Colectomy
Mt Sinai Hospital, New York
Morgan Stanley Children's Hospital, New York
Cohen Children's Medical Center, New Hyde Park
Golisano Children's Hospital SUNY Upstate Medical University, Syracuse
Women and Children's Hospital of Buffalo, Buffalo
Children's Hospital of Pittsburgh of UPMC, Pittsburgh
Children's Hospital of Philadelphia, Philadelphia
John Hopkins Children's Hospital, Baltimore
University of North Carolina at Chapel HIll, Chapel Hill
Emory Children's Center, Atlanta
Nemours Children's Clinic, Jacksonville
Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville
Nationwide Children's Hospital, Columbus
Cincinnati Children's Hospital Medical Center, Cincinnati
Riley Children's Hospital, Indianapolis
Medical College of Wisconsin, Milwaukee
University of Minnesota Medical Center, Minneapolis
UT Southwestern, Dallas
Primary Children's Medical Center (University of Utah), Salt Lake City
UCLA Medical Center, Los Angeles
University of California at San Francisco, San Francisco
Connecticut Children's Medical Center, Hartford
Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago
Children's Hospital of Boston, Boston
Goryeb Children's Hospital / Atlantic Health, Morristown
Hasbro Children's Hospital, Providence
IWK Health Centre, Halifax
Children's Hospital of Eastern Ontario, Ottawa
Hospital for Sick Children, Toronto
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Connecticut Children's Medical Center
OTHER