Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MDCO-2010 in Patients Undergoing Elective Coronary Artery Bypass Graft Surgery

PHASE2CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

November 30, 2010

Primary Completion Date

May 31, 2011

Study Completion Date

June 30, 2011

Conditions

Coronary Artery Bypass GraftCardiopulmonary Bypass

Interventions

DRUG

MDCO-2010

MDCO-2010 solution for infusion. Dosage: Pump priming dose; Loading dose infusion over 6 minutes; Maintenance infusion for duration of surgery

DRUG

Placebo

Commercially available NaCl