Brentuximab Vedotin Plus AVD in Limited-stage Hodgkin Lymphoma

PHASE2CompletedINTERVENTIONAL
Enrollment

34

Participants

Timeline

Start Date

March 31, 2012

Primary Completion Date

January 31, 2015

Study Completion Date

January 31, 2018

Conditions
Hodgkin Lymphoma
Interventions
DRUG

Brentuximab Vedotin

2 doses administered 14 days apart; followed by combination therapy with AVD for 4-6 cycles; 1.2 mg/kg

DRUG

Adriamycin, vinblastine, and dacarbazine

Combination therapy with brentuximab for 4-6 cycles; 25 mg/m2 Adriamycin; 6 mg/m2 Vinblastine; 375 mg/m2 Dacarbazine

Trial Locations (4)

33612

Moffitt Cancer Center, Tampa

02114

Massachusetts General Hosptial, Boston

02115

Dana-Farber Cancer Institute, Boston

02215

Beth Israel Deaconess Medical Center, Boston

All Listed Sponsors
collaborator

Beth Israel Deaconess Medical Center

OTHER

collaborator

Dana-Farber Cancer Institute

OTHER

collaborator

H. Lee Moffitt Cancer Center and Research Institute

OTHER

collaborator

Seagen Inc.

INDUSTRY

lead

Massachusetts General Hospital

OTHER

NCT01534078 - Brentuximab Vedotin Plus AVD in Limited-stage Hodgkin Lymphoma | Biotech Hunter | Biotech Hunter