Study in Healthy Volunteers to Investigate the Effects of Quinidine on the Pharmacokinetics of NKTR-118

PHASE1CompletedINTERVENTIONAL
Enrollment

214

Participants

Timeline

Start Date

March 31, 2012

Primary Completion Date

September 30, 2012

Study Completion Date

September 30, 2012

Conditions
Drug Induced Constipation
Interventions
DRUG

Nektar 118

Oral 25 mg tablet

DRUG

Quinidine

Oral 200 mg tablet

DRUG

Quinidine placebo

Oral Tablet

DRUG

Morphine

10 mg/ml, intravenously

Trial Locations (1)

Unknown

Research Site, Overland Park

Sponsors

Lead Sponsor

All Listed Sponsors
lead

AstraZeneca

INDUSTRY